16.06.2023
Anti-viral property of non-functionalized nanoparticles and nanostructured surfaces
A “hot” area of research – antiviral therapy with nanoparticles and nanostructured surfaces – have been pursued at the international forefront, together with scientists from the Institute of Medical Biology, Polish Academy of Sciences, Łód´z, Poland. n addition, the work involves scientists from National Academy of Sciences of Ukraine – Lashkariov Institiute of Semiconductor Physics NASU, Zabolotny Institute of Microbiology and Virology NASU, Chuiko Institute of Surface Chemistry NASU. Antiviral therapy with nanoparticles and nanostructured surfaces is a rapidly developing branch of modern medicine known as nanomedicine. The main idea of such therapy is the physical (field) action of nano particleson the virus, which prevents the virus from effectively countering such drugs through mutagenesis. Our scientific team proposed the physical model of antiviral activity of non-functionalized nanoparticles based on local-field enhancement effect.
Briefly the model consists on the three steps:
i – nanoparticles adsorbed onto viral surface;
ii – due to local-field enhancement the domains of strong fields arise at the viral surface;
iii – the strong gradients of the field in the domain cause the ponderomotive forces damaging to the molecule-receptors at the viral surfaceup to the whole destroying the viral envelope.
There are the information that pure nanoparticles act effectively to the microbes – bacteria and fungi.